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Article

Association analysis of SIGMAR1 with major depressive disorder and SSRI response.

Neuropharmacology - 1 Jun 2010

Kishi Taro, Yoshimura Reiji, Okochi Tomo, Fukuo Yasuhisa, Kitajima Tsuyoshi, Okumura Takenori, Tsunoka Tomoko, Kawashima Kunihiro, Yamanouchi Yoshio, Kinoshita Yoko, Umene-Nakano Wakako, Naitoh Hiroshi, Nakamura Jun, Ozaki Norio, Iwata Nakao

Abstract excerpt

BACKGROUND: Several investigations have suggested the possible involvement of sigma 1 non-opioid intracellular receptor 1 (sigma 1 receptor) in the pathophysiology of major depressive disorder (MDD). Sigma 1 receptors are also one of the major pharmacological therapeutic targets of selective sero...

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Source

Identifiers

PMID: 20178807
DOI: 10.1016/j.neuropharm.2010.02.013

Genes

SIGMAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20178807-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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