Article
Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.
Psychiatry research - 15 Aug 2012
Kurose Kouichi, Hiratsuka Kazuyuki, Ishiwata Kazuya, Nishikawa Jun, Nonen Shinpei, Azuma Junichi, Kato Masaki, Wakeno Masataka, Okugawa Gaku, Kinoshita Toshihiko, Kurosawa Toru, Hasegawa Ryuichi, Saito Yoshiro
Abstract excerpt
Sexual dysfunction is a major side effect of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs). We conducted a genome-wide association study to identify the genetic factors contributing to the risk of SSRI/SNRI-induced sexual dysfunction by testing 186 320 single nucleotide polymorphism (SNP) markers in a cohort of 201 Japanese major depression patients...
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