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Article

Interactions between dietary fat intake and FASN genetic variation influence LDL peak particle diameter.

Journal of nutrigenetics and nutrigenomics - 1 Jan 2011

Dolley G, Boisclair M E, Lamarche B, Després J P, Bouchard C, Pérusse L, Vohl M C

Abstract excerpt

BACKGROUND: The small, dense LDL phenotype is associated with an increased cardiovascular disease risk. A genome-wide scan performed on the Quebec Family Study (QFS) revealed a quantitative trait locus for LDL peak particle diameter (LDL-PPD) on the 17q21 region. A positional candidate gene - the fatty acid synthase gene (FASN) - encodes a key enzyme in the biogenesis of membrane lipids. FASN may play a role in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21646813
DOI: 10.1159/000327778

Genes

FASN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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