Article
Influences of the phosphatidylcholine transfer protein gene variants on the LDL peak particle size.
Atherosclerosis - 1 Dec 2007
Dolley G, Berthier M T, Lamarche B, Després J P, Bouchard C, Pérusse L, Vohl M C
Abstract excerpt
BACKGROUND: The small, dense LDL phenotype is associated with an increased cardiovascular disease risk. A genome-wide scan performed on 236 nuclear families of the Quebec Family Study (QFS) revealed a quantitative trait locus (QTL) affecting LDL peak particle size (LDL-PPD) and density on the 17q21 region. This region contains the phosphatidylcholine transfer protein gene (PCTP). In the liver, phosphatidylcholine...
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