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Article

Detection of a major gene effect for LDL peak particle diameter and association with apolipoprotein H gene haplotype.

Atherosclerosis - 1 Oct 2005

Bossé Yohan, Feitosa Mary F, Després Jean-Pierre, Lamarche Benoît, Rice Treva, Rao D C, Bouchard Claude, Pérusse Louis, Vohl Marie-Claude

Abstract excerpt

Low-density lipoprotein (LDL) size, a coronary heart disease risk factor, is influenced by both genetic and environmental factors. Results from the Quebec Family Study (QFS) revealed that the LDL peak particle diameter (LDL-PPD) aggregates in families with a heritability coefficient above 50% and is affected by a major quantitative trait locus on chromosome 17q (LOD=6.8). Complex segregation analyses have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16159595
DOI: 10.1016/j.atherosclerosis.2005.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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