Article
Dietary intervention modifies low-density lipoproteins particle size according to genetic variability: a clinical study.
Clinical nutrition ESPEN - 1 Jun 2026
González-Salazar L E, Guizar-Heredia R, Flores-López A, Aguilar-López M, Medina-Vera I, Erazo-Tapia E, Pichardo-Ontiveros E, Orozco-Ruiz X, Vázquez-Manjarrez N, Serralde-Zúñiga A E, Avila-Nava A, González-Garay A, Hernández-Gómez K G, Velázquez-Villegas L A, Noriega L G, Torres N, Tovar A R, Guevara-Cruz M
Abstract excerpt
BACKGROUND & AIMS: An increased number of low-density lipoprotein particles (LDL-P) is a common feature of patients with Metabolic syndrome (MetS). Increasing the size of these particles is one of the primary therapeutic and dietary interventions goals. However, genetic variability, like single nucleotide polymorphisms (SNPs), modulate the response to dietary strategies. Therefore, we hypothesise that the...
Topics
- Adult
- Female
- Humans
- Male
- Middle Aged
- Alpha-Ketoglutarate-Dependent Dioxygenase FTO
- Apolipoproteins E
- ATP Binding Cassette Transporter 1
- Cholesterol, LDL