Article
Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity.
Human genetics - 1 Apr 2013
Frazier-Wood Alexis C, Manichaikul Ani, Aslibekyan Stella, Borecki Ingrid B, Goff David C, Hopkins Paul N, Lai Chao-Qiang, Ordovas Jose M, Post Wendy S, Rich Stephen S, Sale Michèle M, Siscovick David, Straka Robert J, Tiwari Hemant K, Tsai Michael Y, Rotter Jerome I, Arnett Donna K
Abstract excerpt
Specific constellations of lipoprotein particle features, reflected as differences in mean lipoprotein particle diameters, are associated with risk of insulin resistance (IR) and cardiovascular disease (CVD). The associations of lipid profiles with disease risk differ by race/ethnicity, the reason for this is not clear. We aimed to examine whether there were additional genetic differences between racial/ethnic...
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