Article
A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle.
Human genetics - 1 Jun 2010
Nakayama Kazuhiro, Bayasgalan Tumenbayer, Tazoe Fumiko, Yanagisawa Yoshiko, Gotoh Takaya, Yamanaka Kazuhiro, Ogawa Ayumi, Munkhtulga Lkhagvasuren, Chimedregze Ulziiburen, Kagawa Yasuo, Ishibashi Shun, Iwamoto Sadahiko
Abstract excerpt
Recent genome-wide association studies (GWASs) showed that single nucleotide polymorphisms (SNPs) in FADS1/FADS2 were associated with plasma lipid concentrations in populations with European ancestry. We investigated the associations between the SNPs in FADS1/FADS2 and plasma concentrations of triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in two Asian...
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