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Article

Explaining complex codon usage patterns with selection for translational efficiency, mutation bias, and genetic drift.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2011

Shah Premal, Gilchrist Michael A

Abstract excerpt

The genetic code is redundant with most amino acids using multiple codons. In many organisms, codon usage is biased toward particular codons. Understanding the adaptive and nonadaptive forces driving the evolution of codon usage bias (CUB) has been an area of intense focus and debate in the fields of molecular and evolutionary biology. However, their relative importance in shaping genomic patterns of CUB remains...

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Identifiers

PMID: 21646514
DOI: 10.1073/pnas.1016719108
PMCID: PMC3121864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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