Article
Selection on codon bias.
Annual review of genetics - 1 Jan 2008
Hershberg Ruth, Petrov Dmitri A
Abstract excerpt
In a wide variety of organisms, synonymous codons are used with different frequencies, a phenomenon known as codon bias. Population genetic studies have shown that synonymous sites are under weak selection and that codon bias is maintained by a balance between selection, mutation, and genetic drift. It appears that the major cause for selection on codon bias is that certain preferred codons are translated more...
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