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Article

DISC1 is associated with cortical thickness and neural efficiency.

NeuroImage - 15 Aug 2011

Brauns Stefan, Gollub Randy L, Roffman Joshua L, Yendiki Anastasia, Ho Beng-Choon, Wassink Thomas H, Heinz Andreas, Ehrlich Stefan

Abstract excerpt

BACKGROUND: Disrupted in schizophrenia 1 (DISC1) is known to play a major role during brain development and is a candidate gene for schizophrenia. Cortical thickness is highly heritable and several MRI studies have shown widespread reductions of cortical thickness in patients with schizophrenia. Here, we investigated the effects of variation in DISC1 on cortical thickness. In a subsequent analysis we tested...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21642004
DOI: 10.1016/j.neuroimage.2011.05.058
PMCID: PMC3138880

Genes

DISC1

Provenance

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