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Article

The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

23 Aug 2015

Abstract excerpt

BACKGROUND: The disrupted in schizophrenia 1 (DISC1) gene locus was originally identified in a Scottish pedigree with a high incidence of psychiatric disorders that is associated with a balanced t(1;11)(q42.1;q14.3) chromosomal translocation. Here, we investigated whether members of this family carrying the t(1;11)(q42.1;q14.3) translocation have a common brain-related phenotype and whether this phenotype is...

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PMID: 26301809
DOI: 10.1172/jci82636

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