Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complex.

doi:10.1111/j.1753-0407.2011.00131.x

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Article

Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complex.

Journal of diabetes - 1 Sept 2011

Baschal Erin E, Sarkar Suparna A, Boyle Theresa A, Siebert Janet C, Jasinski Jean M, Grabek Katharine R, Armstrong Taylor K, Babu Sunanda R, Fain Pamela R, Steck Andrea K, Rewers Marian J, Eisenbarth George S

Abstract excerpt

BACKGROUND: We recently reported an association between Type 1 diabetes and the telomeric major histocompatibility complex (MHC) single nucleotide polymorphism (SNP) rs1233478. As further families have been analyzed in the Type 1 Diabetes Genetics Consortium (T1DGC), we tested replication of the association and, with more data, analyzed haplotypic associations. METHODS: An additional 2717 case and 1315 control...

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PMID: 21631897
DOI: 10.1111/j.1753-0407.2011.00131.x
PMCID: PMC3610173

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