Article
MHC fine mapping of human type 1 diabetes using the T1DGC data.
Diabetes, obesity & metabolism - 1 Feb 2009
He C, Hamon S, Li D, Barral-Rodriguez S, Ott J
Abstract excerpt
AIM: The human Major Histocompatibility Complex (MHC) is a highly polymorphic genomic region occupying approximately 4 Mb on chromosome 6p21.3. The relationship between human MHC and type 1 diabetes (T1D) has been previously investigated. To fine map the disease locus in this region, we carried out both linkage and association analyses using the Type 1 Diabetes Genetics Consortium data. METHODS: Two-point linkage...
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