Article
Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.
Diabetes, obesity & metabolism - 1 Feb 2009
Valdes A M, Thomson G
Abstract excerpt
AIM: Several studies have indicated that genes in the human leucocyte antigen (HLA) region additional to the HLA class II DRB1-DQB1 contribute to type 1 diabetes (T1D) susceptibility. The aim of this study was to assess if markers in the class III Major Histocompatibility Complex (MHC) region are associated with T1D after accounting for linkage disequilibrium (LD) with DRB1-DQB1. METHODS: We investigated 356...
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