Article
A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study.
Diabetes - 1 Apr 2008
Hakonarson Hakon, Qu Hui-Qi, Bradfield Jonathan P, Marchand Luc, Kim Cecilia E, Glessner Joseph T, Grabs Rosemarie, Casalunovo Tracy, Taback Shayne P, Frackelton Edward C, Eckert Andrew W, Annaiah Kiran, Lawson Margaret L, Otieno F George, Santa Erin, Shaner Julie L, Smith Ryan M, Onyiah Chioma C, Skraban Robert, Chiavacci Rosetta M, Robinson Luke J, Stanley Charles A, Kirsch Susan E, Devoto Marcella, Monos Dimitri S, Grant Struan F A, Polychronakos Constantin
Abstract excerpt
OBJECTIVE: In stage 1 of our genome-wide association (GWA) study for type 1 diabetes, one locus at 16p13 was detected (P = 1.03 x 10(-10)) and confirmed in two additional cohorts. Here we describe the results of testing, in these additional cohorts, 23 loci that were next in rank of statistical significance. RESEARCH DESIGN AND METHODS: Two independent cohorts were studied. The Type 1 Diabetes Genetics Consortium...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.