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Article

Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex.

Genome research - 1 Jul 2011

Vandiedonck Claire, Taylor Martin S, Lockstone Helen E, Plant Katharine, Taylor Jennifer M, Durrant Caroline, Broxholme John, Fairfax Benjamin P, Knight Julian C

Abstract excerpt

The human major histocompatibility complex (MHC) on chromosome 6p21 is a paradigm for genomics, showing remarkable polymorphism and striking association with immune and non-immune diseases. The complex genomic landscape of the MHC, notably strong linkage disequilibrium, has made resolving causal variants very challenging. A promising approach is to investigate gene expression levels considered as tractable...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21628452
DOI: 10.1101/gr.116681.110
PMCID: PMC3129247

Genes

ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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