Article
Unique Allelic eQTL Clusters in Human MHC Haplotypes.
G3 (Bethesda, Md.) - 7 Aug 2017
Lam Tze Hau, Shen Meixin, Tay Matthew Zirui, Ren Ee Chee
Abstract excerpt
The control of gene regulation within the major histocompatibility complex (MHC) remains poorly understood, despite several expression quantitative trait loci (eQTL) studies revealing an association of MHC gene expression with independent tag-single nucleotide polymorphisms (SNPs). MHC haplotype variation may exert a greater effect on gene expression phenotype than specific single variants. To explore the effect...
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