Article
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics - 1 Jan 2008
Horton Roger, Gibson Richard, Coggill Penny, Miretti Marcos, Allcock Richard J, Almeida Jeff, Forbes Simon, Gilbert James G R, Halls Karen, Harrow Jennifer L, Hart Elizabeth, Howe Kevin, Jackson David K, Palmer Sophie, Roberts Anne N, Sims Sarah, Stewart C Andrew, Traherne James A, Trevanion Steve, Wilming Laurens, Rogers Jane, de Jong Pieter J, Elliott John F, Sawcer Stephen, Todd John A, Trowsdale John, Beck Stephan
Abstract excerpt
The human major histocompatibility complex (MHC) is contained within about 4 Mb on the short arm of chromosome 6 and is recognised as the most variable region in the human genome. The primary aim of the MHC Haplotype Project was to provide a comprehensively annotated reference sequence of a single, human leukocyte antigen-homozygous MHC haplotype and to use it as a basis against which variations could be assessed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.