Article

Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells

2023-12-27

Abstract excerpt

<h4>ABTRACT</h4> Computational strategies to extract meaningful biological information from multiomics data are in great demand for effective clinical use. This is most relevant in immune-mediated disorders, where the combined impact of multiple variants is difficult to determine. Regulatory T cells (Tregs), particularly those lineage-committed in the thymus, are essential for immune homeostasis and self-toleranc...

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Literature Corpus work: cc51a940-553f-5a04-9184-f6b6014b959f
DOI: 10.1101/2023.12.27.573411

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