Article
The growth of simian virus 40 (SV40) host range/adenovirus helper function mutants in an African green monkey cell line that constitutively expresses the SV40 agnoprotein.
Journal of virology - 1 Jul 1990
Stacy T P, Chamberlain M, Carswell S, Cole C N
Abstract excerpt
The simian virus 40 T-antigen carboxy-terminal mutants, dlA2459 and dlA2475, are cell line and temperature dependent for growth and plaque formation in monkey kidney cells. Although these mutants did form plaques on BSC-1 cells at 37 degrees C, they were about fivefold less efficient for plaque f...
Topics
- Adenoviruses, Human
- Animals
- Antigens, Polyomavirus Transforming
- Cell Line
- Chlorocebus aethiops
- Genetic Complementation Test
- Mutation
- RNA, Messenger
- RNA, Viral
- Simian virus 40
- Vero Cells
- Viral Plaque Assay
- Virus Replication