Article
Simian virus 40 large T antigen host range domain functions in virion assembly.
Journal of virology - 1 Jul 1994
Spence S L, Pipas J M
Abstract excerpt
The simian virus 40 (SV40) T antigen host range mutants dl1066 and dl1140 display a postreplicative block to plaque formation which suggests a novel role for T antigen late in the viral life cycle. The host range mutants dl1066 and dl1140 are able to grow in and plaque on BSC but not on CV1 monke...
Topics
- Animals
- Antigens, Polyomavirus Transforming
- Blotting, Southern
- Blotting, Western
- Capsid
- Capsid Proteins
- Cell Line
- Centrifugation, Density Gradient
- Chlorocebus aethiops
- DNA, Viral
- Electrophoresis, Gel, Pulsed-Field
- Mutation
