Adenovirus helper function activity of simian virus 40 T antigen mutants.

doi:10.1016/0042-6822(92)90601-k

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Article

Adenovirus helper function activity of simian virus 40 T antigen mutants.

Virology - 1 Aug 1992

Heath C V, Fanning E, Cole C N

Abstract excerpt

The SV40 large T antigen provides a helper function that permits human adenovirus yields in monkey cells to approach those obtained in human cells. The carboxy-terminus of large T antigen is involved in providing this activity. The ability of a large number of SV40 mutants affecting T antigen to...

Topics

Adenoviruses, Human
Animals
Antigens, Polyomavirus Transforming
Cell Line
Chlorocebus aethiops
DNA Mutational Analysis
Gene Expression Regulation, Viral
Humans
In Vitro Techniques
Mutation
Transfection
Viral Plaque Assay
Virus Replication

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