Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors.

doi:10.1128/JVI.72.12.9637-9644.1998

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Article

Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors.

Journal of virology - 1 Dec 1998

Howe A K, Gaillard S, Bennett J S, Rundell K

Abstract excerpt

The simian virus 40 small t antigen (small-t) is required for optimal viral replication and transformation, especially during the infection of nondividing cells, suggesting that the function of small-t is to promote cell cycle progression. The mechanism through which small-t promotes cell growth...

Topics

Adenoviridae
Animals
Antigens, Viral, Tumor
Calcium-Calmodulin-Dependent Protein Kinases
Cell Cycle
Cell Division
Cell Line
Chlorocebus aethiops
Enzyme Activation
Genetic Vectors
Humans
JNK Mitogen-Activated Protein Kinases
MAP Kinase Kinase Kinase 1
Mitogen-Activated Protein Kinases
Mutation
Phosphoprotein Phosphatases
Phosphorylation
Protein Phosphatase 2

Source

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Identifiers

PMID: 9811697
DOI: 10.1128/JVI.72.12.9637-9644.1998
PMCID: PMC110473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9811697-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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