Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of simian virus 40 Vp1 cysteines in virion infectivity.

Journal of virology - 1 Dec 2000

Li P P, Nakanishi A, Tran M A, Salazar A M, Liddington R C, Kasamatsu H

Abstract excerpt

We have developed a new nonoverlapping infectious viral genome (NO-SV40) in order to facilitate structure-based analysis of the simian virus 40 (SV40) life cycle. We first tested the role of cysteine residues in the formation of infectious virions by individually mutating the seven cysteines in the major capsid protein, Vp1. All seven cysteine mutants-C9A, C49A, C87A, C104A, C207S, C254A, and C267L-retained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Capsid
Share to Capsid Proteins
Share to Cysteine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Protein Structure, Secondary

Share to Simian virus 40

Share to Structure-Activity Relationship

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 11070039
DOI: 10.1128/jvi.74.23.11388-11393.2000
PMCID: PMC113244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of simian virus 40 Vp1 cysteines in virion infectivity.PMID 11070039Read ↗

Pairs of Vp1 cysteine residues essential for simian virus 40 infection.Semantic proximity Read ↗

Identification of amino acid residues within simian virus 40 capsid proteins Vp1, Vp2, and Vp3 that are required for their interaction and for viral infection.Semantic proximity Read ↗

The simian virus 40 minor structural protein Vp3, but not Vp2, is essential for infectious virion formation.Semantic proximity Read ↗

Minor Capsid Proteins of Simian Virus 40 Are Dispensable for Nucleocapsid Assembly and Cell Entry but Are Required for Nuclear Entry of the Viral GenomeSemantic proximity Read ↗

Mutational analysis of the carboxyl-terminal region of the SV40 major capsid protein VP1.Semantic proximity Read ↗

Essential role of the Vp2 and Vp3 DNA-binding domain in simian virus 40 morphogenesis.Semantic proximity Read ↗

Cysteine residues in the major capsid protein, Vp1, of the JC virus are important for protein stability and oligomer formation.Semantic proximity Read ↗

A very late viral protein triggers the lytic release of SV40.Semantic proximity Read ↗

Conserved cysteines in Mason-Pfizer monkey virus capsid protein are essential for infectious mature particle formation.Semantic proximity Read ↗

Structural analysis of human immunodeficiency virus type 1 Gag protein interactions, using cysteine-specific reagents.Semantic proximity Read ↗

Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines.Semantic proximity Read ↗

Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.