Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.

Journal of virology - 1 Jan 1990

Shibata R, Miura T, Hayami M, Sakai H, Ogawa K, Kiyomasu T, Ishimoto A, Adachi A

Abstract excerpt

We constructed a full-length molecular clone of simian immunodeficiency virus from an African green monkey. Upon transfection, this clone directed the production of virus particles cytopathic and infectious to human CD4+ leukemia cell lines. Mutations were introduced by recombinant DNA techniques into eight open reading frames of simian immunodeficiency virus from the African green monkey thus far identified. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Mutation

Share to Restriction Mapping

Share to RNA, Messenger

Share to Transcription, Genetic

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2293665
DOI: 10.1128/JVI.64.1.307-312.1990
PMCID: PMC249103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.PMID 2293665Read ↗

Mutational analysis of simian immunodeficiency virus from African green monkeys and human immunodeficiency virus type 2.Semantic proximity Read ↗

Genetic characterization of simian immunodeficiency virus isolated from an African mandrill.Semantic proximity Read ↗

Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).Semantic proximity Read ↗

Assessing genetic-based therapies for AIDS using the simian immunodeficiency virus.Semantic proximity Read ↗

Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cellsSemantic proximity Read ↗

Early replication block of human immunodeficiency virus type 1 in monkey cellsSemantic proximity Read ↗

Generation and characterization of the human immunodeficiency virus type 1 mutants.Semantic proximity Read ↗

A dominant block to HIV-1 replication at reverse transcription in simian cellsSemantic proximity Read ↗

Simian immunodeficiency viruses of African green monkeys.Semantic proximity Read ↗

Fusogenicity of mutant and chimeric proviruses derived from molecular clones of cytopathic and noncytopathic human immunodeficiency virus type 2.Semantic proximity Read ↗

Complete nucleotide sequence of a simian immunodeficiency virus from African green monkeys: a novel type of intragroup divergence.Semantic proximity Read ↗

Transforming functions of Simian Virus 40Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.