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Article

Telomere instability caused by subtelomeric Y' amplification and rearrangements in Saccharomyces cerevisiae (ku70 tel1 and ku70 rad50) double mutants.

Indian journal of experimental biology - 1 May 2011

Ruiz-Gómez Miguel J

Abstract excerpt

Telomeres solve the end-replication problem. Previous results suggested a relation between Yku70/80 and proteins Tell and Rad50 in telomere stabilization. Inactivation of any of these genes lead to a shortening of telomeres, while in ku70 tell or ku70 rad50 double mutants a drastic amplification of Y' elements was found. The biological significance of this observation is not clear. To further characterize Y'...

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PMID: 21615055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Telomere instability caused by subtelomeric Y' amplification and rearrangements in Saccharomyces cerevisiae (ku70 tel1 and ku70 rad50) double mutants.PMID 21615055Read ↗

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The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae.Semantic proximity Read ↗

The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences.Semantic proximity Read ↗

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Telomeric amplicons of <i>SUL1</i> and Y’ in yeast are generated by microhomology-mediated break induced replication occurring <i>in cis</i>Semantic proximity Read ↗

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Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.Semantic proximity Read ↗

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