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Article

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.

Genes & development - 1 Oct 2003

Stellwagen Anne E, Haimberger Zara W, Veatch Joshua R, Gottschling Daniel E

Abstract excerpt

Ku is a conserved DNA end-binding protein that plays various roles at different kinds of DNA ends. At telomeres, Ku is part of the structure that protects the chromosome end, whereas at broken DNA ends, Ku promotes DNA repair as part of the nonhomologous end-joining (NHEJ) pathway. Here, we prese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12975323
DOI: 10.1101/gad.1125903
PMCID: PMC218076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12975323-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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