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In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway.

Genetics - 1 Oct 2009

Marvin Marcus E, Griffin Craig D, Eyre David E, Barton David B H, Louis Edward J

Abstract excerpt

Unlike in meiosis where recombination near telomeres is repressed, subtelomeric regions appear to recombine with each other frequently in vegetative cells with no detrimental consequences. To test whether or not such recombination is prevented in the core of chromosomes for maintenance of genome stability, we measured allelic homologous recombination (HR) along chromosome arms and between different ectopic...

Topics

Chromosome Mapping
Chromosomes, Fungal
DNA, Fungal
DNA-Binding Proteins
Genome, Fungal
Genomic Instability
Mutation
Recombination, Genetic
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Telomere

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Open in PubMed Open full text

Identifiers

PMID: 19652177
DOI: 10.1534/genetics.109.106674
PMCID: PMC2766308

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In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway.PMID 19652177Read ↗

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