Chemokine RANTES promoter dimorphisms and hepatocellular carcinoma occurrence in patients with alcoholic or hepatitis C virus-related cirrhosis.

doi:10.1158/1055-9965.EPI-11-0341

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Chemokine RANTES promoter dimorphisms and hepatocellular carcinoma occurrence in patients with alcoholic or hepatitis C virus-related cirrhosis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2011

Charni Faten, Sutton Angela, Rufat Pierre, Laguillier Christelle, Mansouri Abdellah, Moreau Richard, Ganne-Carrié Nathalie, Trinchet Jean-Claude, Beaugrand Michel, Charnaux Nathalie, Nahon Pierre

Abstract excerpt

BACKGROUND: This study explores the influence of two functional genetic polymorphisms in the regulated on activation in normal T-cell expressed and secreted(RANTES) promoter on the risk of hepatocellular carcinoma (HCC) occurrence in patients with alcoholic or Hepatitis C Virus (HCV)-related cirrhosis. METHODS: RANTES C-28G and G-403A promoter dimorphisms and RANTES serum levels were assessed in 243 HCV-infected...

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PMID: 21610221
DOI: 10.1158/1055-9965.EPI-11-0341

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