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Article

Liver iron, HFE gene mutations, and hepatocellular carcinoma occurrence in patients with cirrhosis.

Gastroenterology - 1 Jan 2008

Nahon Pierre, Sutton Angela, Rufat Pierre, Ziol Marianne, Thabut Gabriel, Schischmanoff Pierre-Olivier, Vidaud Dominique, Charnaux Nathalie, Couvert Philippe, Ganne-Carrie Nathalie, Trinchet Jean-Claude, Gattegno Liliane, Beaugrand Michel

Abstract excerpt

BACKGROUND & AIMS: The influence of HFE gene mutations and liver iron overload on hepatocellular carcinoma (HCC) occurrence in patients with cirrhosis is subjected to controversial results. The aim of this work was to clarify this influence in a large cohort of prospectively followed-up cirrhotic patients classified according to the cause of their liver disease. METHODS: Three hundred one consecutive cirrhotic...

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Share to Carcinoma, Hepatocellular
Share to Hemochromatosis Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C

Share to Histocompatibility Antigens Class I

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Share to Liver Cirrhosis, Alcoholic

Share to Liver Neoplasms

Source

Identifiers

PMID: 18061182
DOI: 10.1053/j.gastro.2007.10.038

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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