Article
Lack of association of some chemokine system polymorphisms with the risks of death and hepatocellular carcinoma occurrence in patients with alcoholic cirrhosis: a prospective study.
European journal of gastroenterology & hepatology - 1 May 2007
Nahon Pierre, Sutton Angela, Rufat Pierre, Faisant Charles, Simon Chantal, Barget Nathalie, Trinchet Jean-Claude, Beaugrand Michel, Gattegno Liliane, Charnaux Nathalie
Abstract excerpt
BACKGROUND: Polymorphisms in genes encoding for the chemokines stromal cell-derived factor-1 (SDF-1)/CXCL12, monocyte chemotactic protein-1 (MCP-1)/CCL2, or for the chemokine receptors, CC chemokine receptor 5 (CCR5) or CC chemokine receptor 2 (CCR2) have been associated with the progression of hepatitis C virus-related liver injury and with various cancer development. Their influence on the prognosis of...
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