Article
A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint.
International journal of radiation oncology, biology, physics - 1 Feb 2012
Kelsey Chris R, Jackson Lauren, Langdon Scott, Owzar Kouros, Hubbs Jessica, Vujaskovic Zeljko, Das Shiva, Marks Lawrence B
Abstract excerpt
PURPOSE: To evaluate whether single nucleotide polymorphisms (SNPs) in the transforming growth factor-β1 (TGFβ1) gene are associated with radiation sensitivity using an objective radiologic endpoint. METHODS AND MATERIALS: Preradiation therapy and serial postradiation therapy single photon emission computed tomography (SPECT) lung perfusion scans were obtained in patients undergoing treatment for lung cancer....
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