Association between transforming growth factor beta1 genetic polymorphism and response to chemoradiotherapy in head and neck squamous cell cancer.

doi:10.1002/hed.21014

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association between transforming growth factor beta1 genetic polymorphism and response to chemoradiotherapy in head and neck squamous cell cancer.

Head & neck - 1 May 2009

Lundberg Marie, Pajusto Mervi, Koskinen Walter J, Mäkitie Antti A, Aaltonen Leena-Maija, Mattila Petri S

Abstract excerpt

BACKGROUND: Transforming growth factor beta (TGF-beta) is a pleiotropic cytokine that has diverse roles in cancer. Rate of production of the major isoform, TGF-beta1, is linked with rs1982073 single nucleotide polymorphism in TGFB1 gene signal sequence. METHODS: Peripheral blood DNA of 175 head and neck squamous cell carcinoma patients were genotyped using real-time PCR and fluorescent probes. The median...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Disease Progression

Share to Follow-Up Studies

Share to Head and Neck Neoplasms

Share to Regression Analysis

Share to Survival Analysis

Share to Transforming Growth Factor beta1

Source

Open in PubMed

Identifiers

PMID: 19260117
DOI: 10.1002/hed.21014

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between transforming growth factor beta1 genetic polymorphism and response to chemoradiotherapy in head and neck squamous cell cancer.PMID 19260117Read ↗

Prognostic value of transforming growth factor beta receptor 1 polymorphisms in patients with oral cancer.Semantic proximity Read ↗

TGFbeta1 genetic polymorphism is associated with survival in head and neck squamous cell carcinoma independent of the severity of chemoradiotherapy induced mucositis.Semantic proximity Read ↗

ATM, BCL2, and TGFβ Gene Polymorphisms as Radiotherapy Outcome Biomarkers in Head and Neck Squamous Cell Carcinoma Patients.Semantic proximity Read ↗

TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy.Semantic proximity Read ↗

Transforming growth factor beta 1 genotype and p16 as prognostic factors in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of the transforming growth factor-β1 gene and overall survival in unresectable locally advanced non-small-cell lung cancer patients treated with radio(chemo)therapy in a Chinese population.Semantic proximity Read ↗

Protective role of TGF-β1 (-509C>T, rs1800469) single-nucleotide polymorphism against radiation toxicities in locally advanced head and neck cancer.Semantic proximity Read ↗

Association Between Head and Neck Cancers and Polymorphisms 869T/C, 509C/T, and 915G/C of the Transforming Growth Factor-β1 Gene: A Meta-Analysis of Case-Control Studies.Semantic proximity Read ↗

Genetic variations in the transforming growth factor-beta pathway as predictors of survival in advanced non-small cell lung cancer.Semantic proximity Read ↗

TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population.Semantic proximity Read ↗

TGFβ1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy.Semantic proximity Read ↗

Impact of TGF-β1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.