Article
No association between TGFB1 polymorphisms and late radiotherapy toxicity: a meta-analysis.
PloS one - 1 Jan 2013
Zhu Mei-Ling, Wang MengYun, Shi Ting-Yan, Li Qiao-Xin, Xi Pan, Xia Kai-Qin, Zheng Leizhen, Wei Qing-Yi
Abstract excerpt
BACKGROUND: Transforming growth factor-beta 1 (TGF-β1) protein may be multifunctional and related to the development of fibrosis, induction of apoptosis, extracellular signaling and inhibition of proliferation in response to radiation-induced DNA damage. Several studies have investigated associations between single nucleotide polymorphisms (SNPs) in the TGFB1 gene and risk of late radiation-induced injury of...
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