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Article

Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients.

International journal of radiation biology - 1 Feb 2003

Quarmby S, Fakhoury H, Levine E, Barber J, Wylie J, Hajeer A H, West C, Stewart A, Magee B, Kumar S

Abstract excerpt

PURPOSE: To investigate whether transforming growth factor beta-1 (TGFbeta1) single nucleotide polymorphisms were associated with the susceptibility of breast cancer patients to severe radiation-induced normal tissue damage. MATERIALS AND METHODS: PCR-RFLP assays were performed for TGFbeta1 gene polymorphisms on DNA obtained from 103 breast cancer patients who received radiotherapy. The G-800A, C-509T, T+869C and...

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PMID: 12569017

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Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients.PMID 12569017Read ↗

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