Article
Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Nov 2003
Andreassen Christian Nicolaj, Alsner Jan, Overgaard Marie, Overgaard Jens
Abstract excerpt
BACKGROUND AND PURPOSE: Single nucleotide polymorphisms (SNPs) in genes related to the biological response to radiation injury may affect clinical normal tissue radiosensitivity. This study investigates whether seven selected SNPs in five candidate genes influence risk of subcutaneous fibrosis and telangiectasia after radiotherapy. PATIENTS AND METHODS: The 41 patients included in this study were given...
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