Article
Candidate gene association analysis of acute lymphoblastic leukemia identifies new susceptibility locus at 11p15 (LMO1).
Carcinogenesis - 1 Sept 2011
Beuten Joke, Gelfond Jonathan A L, Piwkham Duangjai, Pollock Brad H, Winick Naomi J, Collier Anderson B, Tomlinson Gail E
Abstract excerpt
To determine the contribution of susceptibility loci in explaining the genetic basis of acute lymphoblastic leukemia (ALL), we genotyped 29 high-potential candidate genes with 672 tagged single-nucleotide polymorphisms (SNPs) in a sample (163 cases and 251 healthy controls) of Caucasian children. Fifty SNPs in 15 genes were significantly associated with ALL risk at the P < 0.05 level. After correction for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
