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Contributions of IKZF1, DDC, CDKN2A, CEBPE, and LMO1 Gene Polymorphisms to Acute Lymphoblastic Leukemia in a Yemeni Population.

Genetic testing and molecular biomarkers - 1 Oct 2017

Al-Absi Boshra, Razif Muhammad F M, Noor Suzita M, Saif-Ali Riyadh, Aqlan Mohammed, Salem Sameer D, Ahmed Radwan H, Muniandy Sekaran

Abstract excerpt

BACKGROUND: Genome-wide and candidate gene association studies have previously revealed links between a predisposition to acute lymphoblastic leukemia (ALL) and genetic polymorphisms in the following genes: IKZF1 (7p12.2; ID: 10320), DDC (7p12.2; ID: 1644), CDKN2A (9p21.3; ID: 1029), CEBPE (14q11.2; ID: 1053), and LMO1 (11p15; ID: 4004). In this study, we aimed to conduct an investigation into the possible...

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Biomarkers, Tumor
CCAAT-Enhancer-Binding Proteins
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase Inhibitor p18

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Ikaros Transcription Factor

LIM Domain Proteins

Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Identifiers

PMID: 28768142
DOI: 10.1089/gtmb.2017.0084

Genes

IKZF1
DDC
LMO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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