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Article

Current evidence for an inherited genetic basis of childhood acute lymphoblastic leukemia.

International journal of hematology - 1 Jan 2013

Urayama Kevin Y, Chokkalingam Anand P, Manabe Atsushi, Mizutani Shuki

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common cancer in children, and efforts to understand its etiology has followed a paradigm that common genetic variation in the presence of modifiable environmental factors contribute to disease risk. To date, there are numerous reports of candidate gene association studies suggesting an involvement of genetic loci in childhood ALL risk, but the general lack of...

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PMID: 23239135
DOI: 10.1007/s12185-012-1220-9

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