Article
Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Jan 2021
Rifkin S B, Shrubsole M J, Cai Q, Smalley W E, Ness R M, Swift L L, Milne G, Zheng W, Murff H J
Abstract excerpt
Numerous studies have reported an association between genetic variants in fatty acid desaturases (FADS1 and FADS2) and plasma or erythrocyte long chain polyunsaturated fatty acid (PUFA) levels. Increased levels of n-6 PUFAs have been associated with inflammation and several chronic diseases, including diabetes and cancer. We hypothesized that genetic variants of FADS that more efficiently convert precursor n-6...
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