Article
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
PLoS genetics - 1 Jan 2009
Tanaka Toshiko, Shen Jian, Abecasis Gonçalo R, Kisialiou Aliaksei, Ordovas Jose M, Guralnik Jack M, Singleton Andrew, Bandinelli Stefania, Cherubini Antonio, Arnett Donna, Tsai Michael Y, Ferrucci Luigi
Abstract excerpt
Polyunsaturated fatty acids (PUFA) have a role in many physiological processes, including energy production, modulation of inflammation, and maintenance of cell membrane integrity. High plasma PUFA concentrations have been shown to have beneficial effects on cardiovascular disease and mortality. To identify genetic contributors of plasma PUFA concentrations, we conducted a genome-wide association study of plasma...
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