Article
Dynamin-catalyzed membrane fission requires coordinated GTP hydrolysis.
PloS one - 1 Jan 2013
Liu Ya-Wen, Mattila Juha-Pekka, Schmid Sandra L
Abstract excerpt
Dynamin is the most-studied membrane fission machinery and has served as a paradigm for studies of other fission GTPases; however, several critical questions regarding its function remain unresolved. In particular, because most dynamin GTPase domain mutants studied to date equally impair both basal and assembly-stimulated GTPase activities, it has been difficult to distinguish their respective roles in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
