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Article

Transcription factor p53 influences microglial activation phenotype.

Glia - 1 Oct 2011

Jayadev Suman, Nesser Nicole K, Hopkins Stephanie, Myers Scott J, Case Amanda, Lee Rona J, Seaburg Luke A, Uo Takuma, Murphy Sean P, Morrison Richard S, Garden Gwenn A

Abstract excerpt

Several neurodegenerative diseases are influenced by the innate immune response in the central nervous system (CNS). Microglia have proinflammatory and subsequently neurotoxic actions as well as anti-inflammatory functions that promote recovery and repair. Very little is known about the transcriptional control of these specific microglial behaviors. We have previously shown that in HIV-associated neurocognitive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21598312
DOI: 10.1002/glia.21178
PMCID: PMC3143257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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