Article
PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation
2025-12-19
Abstract excerpt
<h4>ABSTRACT</h4> Microglia have been implicated in neurodegeneration, though their role remains unclear, as microglia can perform protective functions or promote neuroinflammation. Numerous studies have found that the transcriptome state of microglia can indicate where they lie along this continuum. To understand regulation of microglia transcriptome state, we considered the transcription factor PPAR8, because i...
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Identifiers and source
- Literature Corpus work
- 05367a5d-cdd1-5fc2-9496-e98b6a2c7248
- DOI
- 10.64898/2025.12.17.692628