Article
Mutagenic response of Fanconi's anemia cells from a defined complementation group after treatment with photoactivated bifunctional psoralens.
Cancer research - 1 Jun 1990
Papadopoulo D, Porfirio B, Moustacchi E
Abstract excerpt
The induction of mutants at the hypoxanthine-guanine phosphoribosyltransferase and Na+/K+ ATPase loci by photoaddition of two bifunctional psoralens was compared in normal and in Fanconi's anemia lymphoblasts from the genetic complementation group A. For the two loci, the frequency of mutants was...
Topics
- Anemia, Aplastic
- Cell Survival
- Fanconi Anemia
- Furocoumarins
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Methoxsalen
- Mutation
- Sodium-Potassium-Exchanging ATPase
- Thioguanine
- Trioxsalen
- Ultraviolet Therapy
