[Fanconi's anemia: in vitro tests for the individualization of heterozygotes].

Article

[Fanconi's anemia: in vitro tests for the individualization of heterozygotes].

Giornale italiano di medicina del lavoro - 1 Jan 2000

Farulla A, Monaco E, Corrao C R, Cardoni F, Simonazzi S, Dallapiccola B

Abstract excerpt

Fanconi's anaemia (FA) is an autosomal recessive mutation associated with constitutional chromosome aberrations. Patient's cells show increased susceptibility to different mutagens, especially bifunctional alkylating agents. Asymptomatic heterozygotes have a population prevalence of 1 in 300, and...

Topics

Anemia, Aplastic
Fanconi Anemia
Genetic Carrier Screening
Humans
Mutation

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