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Article

The mutagenic processing of psoralen photolesions leaves a highly specific signature at an endogenous human locus.

Journal of molecular biology - 17 Nov 1995

Laquerbe A, Guillouf C, Moustacchi E, Papadopoulo D

Abstract excerpt

To assess the role of a given genotoxic agent in the etiology of human cancers, it is useful to establish the mutational specificity of this agent. The aim of this study was to investigate whether the processing of psoralen photolesions, interstrand cross-links (CL) and monoadducts (MA), leaves a specific molecular signature in the mutational events produced at an endogenous locus, HPRT. Human lymphoblasts were...

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Identifiers

PMID: 7473757
DOI: 10.1006/jmbi.1995.0597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The mutagenic processing of psoralen photolesions leaves a highly specific signature at an endogenous human locus.PMID 7473757Read ↗

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Genotoxic potential of psoralen cross-links versus monoadducts in normal human lymphoblasts.Semantic proximity Read ↗

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Implications of results of molecular epidemiology on DNA adducts, their repair and mutations for mechanisms of human cancer.Semantic proximity Read ↗

UV-induced photolesions, their repair and mutations.Semantic proximity Read ↗

HPRT gene expression differs in mutants derived from normal and Fanconi anemia cells: analysis of spontaneous and psoralen-photoinduced mutants.Semantic proximity Read ↗

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Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomeraseSemantic proximity Read ↗

Asymmetric recognition of psoralen interstrand crosslinks by the nucleotide excision repair and the error-prone repair pathways.Semantic proximity Read ↗

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