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Article

Photochemotherapy using pyridopsoralens.

Biochimie - 1 Jan 2000

Dubertret L, Averbeck D, Bisagni E, Moron J, Moustacchi E, Billardon C, Papadopoulo D, Nocentini S, Vigny P, Blais J

Abstract excerpt

Aiming to decrease the acute side effects and genotoxic hazards of PUVA, pyrido (3,4-C) psoralen (PP) and 7-methyl pyrido (3,4-C) psoralen (MPP) were synthesized and studied. Their UVA maximum absorption lies at 325 and 330 nm, respectively. Their photostability is comparable to that of 8-MOP. They complex to DNA in the dark, and, in the presence of UVA, produce only monoadditions to DNA, as shown by fluorescence...

Topics

5-Methoxypsoralen
Animals
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
Erythema
Furocoumarins
Humans
Methoxsalen
Mutagenicity Tests
Mutation
PUVA Therapy
Pain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Photochemistry

Pigmentation Disorders

Skin Neoplasms

Source

Identifiers

PMID: 3899194
DOI: 10.1016/s0300-9084(85)80090-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3899194-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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