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Article

Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations.

Genetics - 1 Mar 1990

Su J Y, Belmont L, Sclafani R A

Abstract excerpt

The CDC8 gene of Saccharomyces cerevisiae encodes deoxythymidylate (dTMP) kinase and is required for nuclear and mitochondrial DNA replication in both the mitotic and meiotic cell cycles. All cdc8 temperature-sensitive mutants are partially defective in meiotic and mitochondrial functions at the permissive temperature. In a study of revertants of temperature-sensitive cdc8 mutants, the SOE201 and SOE1 mutants...

Topics

Alleles
Base Sequence
Chromosomes, Fungal
DNA Replication
DNA, Fungal
Genes, Fungal
Molecular Sequence Data
Nucleoside-Phosphate Kinase
Phosphotransferases
RNA, Transfer, Amino Acid-Specific
RNA, Transfer, Glu

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Restriction Mapping

Saccharomyces cerevisiae

Sequence Homology, Nucleic Acid

Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2155851
DOI: 10.1093/genetics/124.3.523
PMCID: PMC1203946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2155851-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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